Respiratory system
Respiratory system


Pulmonary veno-occlusive disease

Definition:
A rare form of primary pulmonary hypertension (high blood pressure in the blood vessels of the lungs) in which progressive obstruction of the pulmonary veins leads to elevated blood pressure in the arteries of the lungs.

Alternative Names:

Pulmonary vaso-occlusive disease



Causes, incidence, and risk factors:

In most cases, the cause is unknown, but it may be related to a viral infection. It may occur as a complication of certain connective tissue diseases, such as lupus or CREST, or as a complication of certain blood cancers (leukemia or lymphoma) or chemotherapy.

The disorder is most common amongst children and young adults. Progression of the disease leads to narrowed pulmonary veins, pulmonary hypertension, congestion, and edema (swelling) of the lungs.




Review Date: 4/30/2002
Reviewed By: David A. Kaufman, M.D., Pulmonary & Critical Care Medicine, University of Pennsylvania Medical Center, Philadelphia, PA. Review provided by VeriMed Healthcare Network.

The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed physician should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. Copyright 2003 A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.