The treatment depends upon the stage of the cancer. For small cell cancer, chemotherapy and radiation are usually used in limited stage disease (when the disease is confined to the chest ). Studies have shown that giving chemotherapy and radiation therapy at the same time is better than giving one after the other. Chemotherapy alone is used for extensive stage disease. In some cases where a patient with limited stage disease has only one small tumor, the tumor will be surgically removed, followed by chemotherapy. However, very few patients with small cell lung cancer are candidates for surgery. Some patients with limited stage disease may need radiation to the entire brain after they have completed chemotherapy and radiation to the chest. This is known as prophylactic cranial irradiation (PCI).
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