Whipple’s disease

Disease	Injury	Nutrition	Poison

Special Topic	Surgery	Symptoms	Test

Whipple’s disease

Alternative Names:

Intestinal lipodystrophy

Treatment:

Patients should receive prolonged antibiotic therapy with a drug that can treat infections of the brain and central nervous system. If symptoms reappear during therapy, patients may require a change in their antibiotic regimen.

Relapses can occur after therapy has been completed, requiring close patient monitoring.

Patients who experience nutritional deficiencies caused by the malabsorption will receive treatment with appropriate dietary supplements.

Expectations (prognosis):

Without treatment, the condition is usually fatal. Treatment improves the chance of a good outcome.

Complications:

Nutritional deficiencies
Weight loss
Reappearance of symptoms, suggesting drug resistance

Calling your health care provider:

Call your health care provider if you have persistent abdominal pain and diarrhea.

If you are being treated for Whipple's disease, call your health care provider if symptoms worsen or do not improve, if symptoms reappear, or if new symptoms develop.

Review Date: 12/27/2002
Reviewed By: Eleftherios Mylonakis, M.D., Division of Infectious Disease, Massachusetts General Hospital, Boston, MA. Review provided by VeriMed Healthcare Network.

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