Digestive system
Digestive system
Upper gastrointestinal system
Upper gastrointestinal system


Gastroesophageal reflux disease

Definition:
Gastroesophageal reflux disease (GERD) is when food or liquid travels from the stomach back up into the esophagus (the tube from the mouth to the stomach). This partially digested material is usually acidic and can irritate the esophagus, often causing heartburn and other symptoms.

Alternative Names:
Peptic esophagitis; Reflux esophagitis; GERD; Heartburn - chronic

Causes, incidence, and risk factors:

Gastroesophageal reflux is a common condition that often occurs without symptoms after meals. In some people, the reflux is related to a problem with the lower esophageal sphincter, a band of muscle fibers that usually closes off the esophagus from the stomach. If this sphincter doesn't close properly, food and liquid can move backward into the esophagus and may cause the symptoms.

Some conditions are associated with incompetent esophageal sphincters, including pregnancy, hiatal hernia, obesity, recurrent or persistent vomiting and nasogastric tubes. Risk factors for reflux include previous esophageal surgery or esophageal stricture.




Review Date: 9/23/2002
Reviewed By: A.D.A.M. editorial. Previous review: Andrew J. Muir, M.D. M.H.S., Division of Gastroenterology, Duke University Medical Center, Durham, NC. Review provided by VeriMed Healthcare Network (4/25/02).

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