Insulin production and diabetes
Insulin production and diabetes


Metabolic acidosis

Definition:

Metabolic acidosis is a disturbance of the body acid-base balance in which there is excessive acidity of the blood. Metabolic acidosis can occur as a result of many different diseases, such as kidney failure, poisoning, diabetic ketoacidosis (DKA), and shock.

Many of these conditions are life-threatening. In addition, metabolic acidosis, if severe, may lead to shock or death. In some situations, metabolic acidosis can be a mild, chronic condition.



Alternative Names:

Acidosis - metabolic



Causes, incidence, and risk factors:

Many different diseases and medical conditions can lead to metabolic acidosis. For example, diabetes mellitus type I (juvenile diabetes), when out of control, leads to diabetic ketoacidosis.

Kidney failure is another important cause of metabolic acidosis. Ingestion of toxic substances, such as antifreeze or excessive amounts of aspirin, can also lead to metabolic acidosis. Shock (extremely low blood pressure) can also cause this condition.




Review Date: 1/26/2002
Reviewed By: David A. Kaufman, M.D., Pulmonary & Critical Care Medicine, University of Pennsylvania Medical Center, Philadelphia, PA. Review provided by VeriMed Healthcare Network.

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