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Felty’s syndrome

Definition:
A disorder characterized by rheumatoid arthritis, an enlarged spleen, a decreased white blood cell count, and recurrent infection.

Causes, incidence, and risk factors:
The cause of Felty’s syndrome is unknown. It is a variant of rheumatoid arthritis and is more common in people who have had rheumatoid arthritis for a long time. People with this syndrome suffer from an increased incidence of infection associated with the low white blood cell count.

Review Date: 12/1/2001
Reviewed By: Birgit Kovacs, M.D., Division of Rheumatology, University of Pennsylvania Medical Center, Philadelphia, PA. Review provided by VeriMed Healthcare Network.

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