Hospitalization is required initially to administer intravenous antibiotics. Long-term, high-dose antibiotic therapy is required to eradicate the bacteria from the heart chambers and vegetations on the valves. Therapy up to 6 weeks is not uncommon. The chosen antibiotic must be specific for the organism causing the condition. This is determined by the blood culture and the sensitivities tests.
If heart failure develops as a result of damaged heart valves, surgery to replace the affected heart valve may be indicated.
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