Central nervous system
Central nervous system


Generalized tonic-clonic seizure

Alternative Names:
Seizure - tonic-clonic; Seizure - grand mal; Grand mal seizure; Seizure - generalized

Symptoms:

Many patients have an aura (sensory warning sign) preceding the seizure. This can include a visual, taste, smell, sensory, or other hallucination or dizziness.

The seizure itself involves: Almost all people experience loss of consciousness, and most people experience both tonic and clonic muscle activity.

After the seizure:
  • the person usually begins breathing normally when the seizure is over
  • arousable but sleepy for one hour or longer
  • loss of memory (amnesia) regarding events surrounding the seizure episode
  • headache
  • drowsiness
  • confusion, temporary and mild
  • may be weak for 24-48 hours following seizure (Todd's paralysis)


Signs and tests:

Diagnosis of a grand mal seizure is based on the symptoms and excluding other medical problems that can look like a seizure (such as heart arrythmia). A neuromuscular examination may or may not reveal neurologic deficits (decreases in brain functions) when the person is not actively having seizures.

An EEG may show characteristic changes and in some cases may show the focus (location of the cause of the seizure). An EEG can be normal in between seizures and a normal EEG does not rule out a seizure disorder.

Tests for the cause may include various blood tests (depending on the suspected cause), including:

Tests for the cause may include procedures such as: Disorders that may cause symptoms resembling seizures include transient ischemic attacks, rage, or panic attacks.


Review Date: 11/21/2002
Reviewed By: Joseph V. Campellone, M.D., Division of Neurology, Cooper Hospital/University Medical Center, Camden, NJ. Review provided by VeriMed Healthcare Network.

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