Central nervous system
Central nervous system


Progressive supranuclear palsy

Alternative Names:
Dementia-nuchal dystonia; Richardson-Steele-Olszewski syndrome; Palsy - progressive supranuclear

Symptoms:
  • Repeated falls
  • Loss of coordination, unsteady gait (walking pattern)
  • Stiffness and rigid movement in the neck, trunk, arms, legs
  • Difficulty swallowing
  • May have a tremor
  • Pain or difficulty with bending the neck up or down
  • Slow or stiff movements
  • Vision difficulty
    • Unable to look up or down without bending the neck
  • Changes in facial expression
  • Generalized slowness of all movement (bradykinesia) with strength relatively preserved
  • Speech difficulties
    • Slow speech
    • Poor enunciation
    • Low voice volume
  • Dementia, mild
    • Forgetfulness
    • Slowed thought processes
    • Apathy (indifference)
    • Difficulty manipulating knowledge
  • Personality changes, vague and mild


Signs and tests:

A neurological examination may show Parkinsonian movements with typical stiffness and lack of coordination. Dementia is mild. Eye movements are limited, particularly vertical movements. However, vision, hearing, sensation, and voluntary control of movement remain intact.

Tests may be done to rule out other diseases. An MRI might show shrinking of the brainstem.




Review Date: 7/28/2002
Reviewed By: Elaine T. Kiriakopoulos, M.D., MSc, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard University, Boston, MA. Review provided by VeriMed Healthcare Network.

The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed physician should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. Copyright 2003 A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.