Histoplasmosis, disseminated in HIV patient
Histoplasmosis, disseminated in HIV patient


Skin lesion of Histoplasmosis

Treatment:
The mainstay of treatment includes antifungal agents such as amphotericin B, itraconazole, and ketoconazole. Antifungals may be given intravenously depending on the form or stage of disease. In individuals with disseminated disease, long-term suppression with oral antifungal agents may be used.

Expectations (prognosis):
Prognosis depends on the clinical form of histoplasmosis and the immune system status of the individual. The death rate is highest in disseminated histoplasmosis.

Complications:
  • Secondary (bacterial) skin infection
  • Complications of medications (For instance, amphotericin B can have severely unpleasant side effects.)


Calling your health care provider:

The skin manifestations of histoplasmosis are varied and may be similar to skin findings seen in other infections or illnesses. Notify your health care provider if you develop any suspicious lesions on your skin so that you may be appropriately evaluated.




Review Date: 8/7/2002
Reviewed By: Camille Kotton, M.D., Infectious Diseases Division, Massachusetts General Hospital and Brigham and Women's Hospital, Boston, MA. Review provided by VeriMed Healthcare Network.

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