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Necrotizing enterocolitis |
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| Definition: | An acquired disease, primarily in premature infants or sick newborns, in which intestinal tissue dies.
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| Causes, incidence, and risk factors: | In necrotizing enterocolitis, the lining of the intestinal wall dies and the tissue sloughs off. The cause for this disorder is unknown, but it is thought that a decreased blood flow to the bowel keeps the bowel from producing the normal protective mucus. Bacteria in the intestine may also be a causative factor. Risk factors include small, premature infants, outbreaks among other infants in a nursery (suggesting an infectious cause), the feeding of concentrated formulas, and infants who have received blood exchange transfusions.
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Review Date: 12/3/2001
Reviewed By: Andrew J. Muir, M.D. M.H.S., Division of Gastroenterology, Duke University Medical Center, Durham, NC. Review provided by VeriMed Healthcare Network.
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