Megaloblastic anemia - view of red blood cells
Megaloblastic anemia - view of red blood cells


Lack of intrinsic factor

Definition:
Intrinsic factor is a natural substance normally present in the stomach. It is essential to the digestion of vitamin B-12. Lack of intrinsic factor leads to pernicious anemia and vitamin B-12 deficiency.

Babies that are born without intrinsic factor cannot properly absorb vitamin B-12 starting around 6 months of age, while the juvenile type tends to manifest itself at an age greater than 10 years.

Alternative Names:
Intrinsic factor - lack of


Review Date: 6/2/2003
Reviewed By: Scott Howard, M.D., M.S., Department of Pediatric Hematology/Oncology, St. Jude Children’s Research Hospital, Memphis, TN. Review provided by VeriMed Healthcare Network.

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