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| Alternative Names: | Androgen insensitivity syndrome
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| Treatment: | For complete testicular feminization:- If testicular tissue is found in the abdomen or in the inguinal canal during childhood, it might not be removed at that time. Once puberty and growth are complete, the testis may be removed because it may develop cancer like any undescended testicle. In addition, gonadoblastomas are cancers that occur almost exclusively in XY gonads of people with abnormalities of sexual differentiation.
- Estrogen replacement after puberty.
- Support of gender identity.
For incomplete testicular feminization:- Treatment and gender assignment can be a very complex issue, and must be individualized with great care.
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| Expectations (prognosis): | Infertility is expected. Otherwise, the outlook for complete testicular feminization is good if at-risk testicular tissue is removed at the proper time. The outlook for incomplete testicular feminization varies greatly depending on the presence and degree of ambiguous genitalia.
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| Complications: | Complications include testicular cancer, infertility, and complex psychosocial issues.
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| Calling your health care provider: | Call your health care provider if you have any signs or symptoms suggestive of the syndrome.
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Review Date: 12/17/2001
Reviewed By: Alan Greene, MD, Chief Medical Officer, A.D.A.M.
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The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed physician should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. Copyright 2003 A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.
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