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| Treatment: | - Supplements containing nicotinamide are often the main treatment. This can effectively treat the rash, and can sometimes treat the uncoordination and psychiatric symptoms.
- A high protein diet is recommended.
- Avoiding sun exposure by wearing protective clothing and using a sunscreen of 15 factor or higher is recommended.
- Psychiatric treatment, such as the use of antidepressants or mood stabilizers, may be needed if mood swings or psychiatric problems occur.
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| Expectations (prognosis): | Most people with this disorder can expect a normal lifespan with no disability. Rarely, there have been reports of severe bouts of neurologic disease and even deaths in families with this disorder.
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| Complications: | There are usually no complications. The minority of people who develop symptoms can experience rash, uncoordinated movements, and less frequently psychiatric symptoms.
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| Calling your health care provider: | Call for an appointment with your health care provider if you have symptoms suggestive of this condition, particularly if you have a family history of Hartnup disorder. Genetic counseling is recommended if you have a family history of this condition and are planning a pregnancy.
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Review Date: 11/8/2002
Reviewed By: David G. Brooks, M.D., Ph.D., Division of Medical Genetics, University of Pennsylvania Medical Center, Philadelphia, PA. Review provided by VeriMed Healthcare Network.
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