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Hallervorden-Spatz disease |
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| Definition: | Hallervorden-Spatz disease is an inherited, degenerative disease that begins in childhood and involves progressive muscle rigidity, weakness, spasticity, and dementia.
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| Causes, incidence, and risk factors: | The majority of cases occur in families with a history of the disorder. The pattern of inheritance suggests that this condition is caused by a recessive gene (which means a child needs defective copies of the gene from both parents) located on chromosome 20p.
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Review Date: 7/28/2002
Reviewed By: Elaine T. Kiriakopoulos, M.D., MSc, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard University, Boston, MA. Review provided by VeriMed Healthcare Network.
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