Creams and ointments are generally no help in treating onychomycosis. Recently, however, a nail lacquer (called Penlac) has been marketed and may be helpful in some patients. Oral medications -- such as Sporanox (itraconazole) or Lamisil (terbinafine) -- may be taken for several months. While these medicines may clear the fungus in about half of all patients, they can cause numerous side effects. Many people are not able to take these medications because of other medications that they are taking, or other medical problems. Nails grow slowly, so even if treatment is successful, a new, clearer nail may take up to one year to replace the old nail.
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