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Stroke
Stroke
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Stroke secondary to FMD

Definition:
Damage to brain tissue caused by fibromuscular dysplasia, an inherited disorder that leads to the destruction of arterial blood vessels which can cause bleeding in the brain.

Alternative Names:
Fibromuscular dysplasia - stroke secondary to

Causes, incidence, and risk factors:

Stroke secondary to fibromuscular dysplasia (FMD) primarily affects women, especially those older than 50.

FMD is an inherited disorder involving the ongoing destruction of arterial blood vessels. There are areas of increased muscle and fibrous tissue in the wall of the affected arteries, which alternate with enlarged (dilated) areas where the tissue has been destroyed. This irregularity in the arteries increases the risk for stroke.

The disease may affect the neck arteries that supply blood to the brain (carotid) or the arteries within the brain (cerebral) and cause stroke. It may also affect the following arteries:

  • kidneys (renal)
  • intestinal tract (mesenteric)
  • heart (coronary)
  • groin (iliac)

Secondary symptoms include high blood pressure, leg pain, heart attack, kidney failure, and other disorders.

Risks include a personal or family history of FMD.



Review Date: 7/28/2002
Reviewed By: Elaine T. Kiriakopoulos, M.D., MSc, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard University, Boston, MA. Review provided by VeriMed Healthcare Network.

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