Muscle aches and pains are common and can involve more than one muscle at the same time. Muscle pain can also involve the soft tissues that surround muscles. These structures, which are often referred to as connective tissues, include ligaments, tendons, and fascia (thick bands of tendons).

See also muscle cramps and joint pain.

Muscle pain is most frequently related to tension, overuse, or muscle injury from exercise or physically demanding work. In these situations, the muscle pain tends to involve specific muscles and starts during or just after the activity. It is usually obvious to you which activity is causing this type of muscle pain.

Muscle pain can also be a sign of conditions affecting your whole body, like some infections (including the flu) and disorders that affect connective tissues throughout the body (such as lupus).

One common cause of muscle aches and pains is fibromyalgia, a condition that includes tenderness in your muscles and surrounding soft tissue, sleep difficulties, fatigue, headaches, and occasionally feelings of depression or anxiety.

• Tension or stress
• Overuse: using a muscle too much, too soon, too often
• Injury or trauma including sprains and strains

• Polymyositis
• Dermatomyositis
• Lupus
• Fibromyalgia
• Polymyalgia rheumatica
• Infections including an abscess in the muscle, Trichinosis (roundworm), Influenza (the flu), Lyme disease, Malaria, Rocky Mountain spotted fever, Polio, and many others
• Electrolyte imbalances like too little potassium or calcium
• Rhabdomyolysis
• Drugs including cocaine; statins for lowering cholesterol (such as atorvastatin, simvastatin, and lovastatin); ACE inhibitors for lowering blood pressure (such as enalapril and captopril); and many others