Vitiligo, drug induced
Vitiligo, drug induced
Vitiligo on the face
Vitiligo on the face
Incontinentia pigmenti on the leg
Incontinentia pigmenti on the leg
Incontinentia pigmenti on the leg
Incontinentia pigmenti on the leg
Hyperpigmentation 2
Hyperpigmentation 2
Post-inflammatory hyperpigmentation - calf
Post-inflammatory hyperpigmentation - calf
Hyperpigmentation w/malignancy
Hyperpigmentation w/malignancy
Post-inflammatory hyperpigmentation 2
Post-inflammatory hyperpigmentation 2


Skin - abnormally dark or light

Definition:
Skin that has turned darker or lighter than normal. See also skin color, patchy.

Alternative Names:
Hyperpigmentation; Hypopigmentation

Considerations:
Normal skin contains cells called melanocytes that produce the brown skin-coloring pigment melanin. There are several conditions in which melanocytes are either abnormal or abnormally distributed. Most skin conditions that cause discoloration are harmless.

A pale area of the skin is the result of fewer or less active melanocytes than usual, whereas a darker area (or area that tans more easily) indicates more numerous or more active melanocytes.

Sometimes mistaken for a suntan, bronzing of the skin often develops gradually starting at pressure points such as the elbows, knuckles, and knees and spreading from there. It is also seen in the creases of the soles of the feet and the palms of the hands. The bronze color can range from light to dark (in fair skinned people) with the intensity often a function of the underlying cause.

There are several types of benign hyperpigmentation that occur normally; however, any persistent hyperpigmentation that has not been medically explained should be seen by a dermatologist.

Common Causes:
  • exposure to the sun
  • medications
  • endocrine diseases such as Addison's syndrome
  • vitiligo



Review Date: 11/11/2001
Reviewed By: Michael Lehrer, M.D., Department of Dermatology, University of Pennsylvania Medical Center, Philadelphia, PA. Review provided by VeriMed Healthcare Network.

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